What is osteocel made of?
What is osteocel made of?
It is comprised of cancellous bone rich in viable cells, combined with demineralized bone matrix from the same donor. The retained cells are naturally adherent to the surface of the cancellous bone and consist of mesenchymal stem cells (MSCs), osteoprogenitors, osteoblasts and other cells along the osteogenic lineage.
Is osteocel FDA approved?
NuVasive and all establishments that process Osteocel are registered with the FDA and are accredited by the AATB.
What is cellular bone matrix?
Cellular bone matrices (CBM) are allograft products that provide three components essential to new bone formation: an osteoconductive scaffold, extracellular growth factors for cell proliferation and differentiation, and viable cells with osteogenic potential.
What is demineralized bone matrix in spinal fusion?
Demineralized bone matrix (DBM) could be successfully used as a potential graft extender, enhancer or substitute. Spinal surgeons can take advance of DBMs osteoinductivity and osteoconductivity and achieve good results in spinal fusion, with a significantly lower complication rate and results similar to these of ICBG.
What is osteocel pro?
Osteocel is a comprehensive bone graft developed to mimic the properties of a patient’s own bone. Osteocel provides a complete and physiologic bone graft that contains all of the necessary components for bone growth: the cells, the signals, and the scaffold. Osteocel plus. Osteocel pro.
What is a ViviGen bone graft?
ViviGen is a cellular allograft intended for repair or reconstruction of musculoskeletal defects. ViviGen is being utilized in fusion, nonunion, and malunion for foot/ankle or long bone trauma in patients with compromised biology.
How do you use vivigen?
Open peel pouch and aseptically present the ported graft pouch directly to a Sterile Team Member. Sterile Team Member: Completely submerge ported graft pouch in warm sterile isotonic solution. Continue thawing until the contents of the pouch flow freely (no more than 5 minutes).
What is Trinity bone graft?
Trinity is a cryopreserved allograft consisting of cancellous bone with, according to the company, “viable cells retained within that matrix and a demineralized cortical bone component. It possesses all three of the key properties for successful bone grafting, which makes it an ideal autograft substitute.”
What is ViviGen allograft?
What three components make up ViviGen cellular bone matrix?
it is comprised of viable cryopreserved corticocancellous bone matrix and demineralized bone. These three components of Vivigen provide the properties necessary for bone repair that include osteoinductive signals, osteoconductive bone scaffolds, and osteogenic cells.
Where does demineralized bone matrix come from?
Demineralized bone matrix (DBM) is prepared by decalcification of cortical bone. It is less immunogenic than allograft bone graft. The active components consists of several glycoproteins including BMPs.
How does demineralized bone matrix work?
Demineralized Bone Matrix (DBM) is a type of bone graft alternative that is processed from human allograft bone. DBM is processed by removing the mineral component of bone with acid, leaving behind the extracellular matrix composed of collagen and non-collagenous proteins, including the endogenous growth factors.
